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Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathwayKUN WANG; SHIYONG CHEN; WEN XIE et al.Biochemical pharmacology. 2008, Vol 75, Num 11, pp 2204-2213, issn 0006-2952, 10 p.Article

Multiple Substrate Binding by Cytochrome P450 3A4 : Estimation of the Number of Bound Substrate MoleculesKAPELYUKH, Yury; PAINE, Mark J. I; MARECHAL, Jean-Didier et al.Drug metabolism and disposition. 2008, Vol 36, Num 10, pp 2136-2144, issn 0090-9556, 9 p.Article

Comparative Study of Hop-Containing Products on Human Cytochrome P450-Mediated MetabolismFOSTER, Brian C; KEARNS, Nikia; ARNASON, John T et al.Journal of agricultural and food chemistry (Print). 2009, Vol 57, Num 11, pp 5100-5105, issn 0021-8561, 6 p.Article

Dexamethasone as a probe for CYP3A4 metabolism: evidence of gender effectPUISSET, F; CHATELUT, E; SPARREBOOM, A et al.Cancer chemotherapy and pharmacology. 2007, Vol 60, Num 2, pp 305-308, issn 0344-5704, 4 p.Article

Potential Strategies for Minimizing Mechanism-Based Inhibition of Cytochrome P450 3A4ZHOU, Shu-Feng.Current pharmaceutical design. 2008, Vol 14, Num 10, pp 990-1000, issn 1381-6128, 11 p.Article

Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesisKUMAR, Santosh; HONG LIU; HALPERT, James R et al.Drug metabolism and disposition. 2006, Vol 34, Num 12, pp 1958-1965, issn 0090-9556, 8 p.Article

Principal Component Analysis of CYP2C9 and CYP3A4 Probe Substrate/Inhibitor PanelsNATH, Abhinav; ATKINS, William.Drug metabolism and disposition. 2008, Vol 36, Num 11, pp 2151-2155, issn 0090-9556, 5 p.Article

Influence of Solute Carriers on the Pharmacokinetics of CYP3A4 ProbesFRANKE, R. M; BAKER, S. D; MATHIJSSEN, R. H et al.Clinical pharmacology and therapeutics. 2008, Vol 84, Num 6, pp 704-709, issn 0009-9236, 6 p.Article

Computational approaches that predict metabolic intermediate complex formation with CYP3A4 (+b5)JONES, David R; EKINS, Sean; LANG LI et al.Drug metabolism and disposition. 2007, Vol 35, Num 9, pp 1466-1475, issn 0090-9556, 10 p.Article

Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl EtherSRIDAR, Chitra; KENT, Ute M; NOON, Kate et al.Drug metabolism and disposition. 2008, Vol 36, Num 11, pp 2234-2243, issn 0090-9556, 10 p.Article

Comparative Study of Hops-Containing Products on Human Cytochrome P450-Mediated MetabolismFOSTER, Brian C; ARNASON, John T; SALEEM, Ammar et al.Journal of agricultural and food chemistry (Print). 2011, Vol 59, Num 9, pp 5159-5163, issn 0021-8561, 5 p.Article

Estrogens and antiestrogens activate hPXRMNIF, Wissem; PASCUSSI, Jean-Marc; PILLON, Arnaud et al.Toxicology letters. 2007, Vol 170, Num 1, pp 19-29, issn 0378-4274, 11 p.Article

Assessment of human pregnane X receptor involvement in pesticide-mediated activation of CYP3A4 geneMATSUBARA, Tsutomu; NORACHARTTIYAPOT, Wachiraporn; TORIYABE, Takayoshi et al.Drug metabolism and disposition. 2007, Vol 35, Num 5, pp 728-733, issn 0090-9556, 6 p.Article

Effect of honey on CYP3A4, CYP2D6 and CYP2C19 enzyme activity in healthy human volunteersTUSHAR, Tewari; VINOD, Thomas; RAJAN, Sundaram et al.Basic & clinical pharmacology & toxicology (Print). 2007, Vol 100, Num 4, pp 269-272, issn 1742-7835, 4 p.Article

Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p' -1,1,1, -trichloro -2,2 -bis (p -chlorophenyl )ethaneMEDINA-DIAZ, Irma M; ARTEAGA-ILLAN, Georgina; DE LEON, Mario Bermudez et al.Drug metabolism and disposition. 2007, Vol 35, Num 1, pp 95-102, issn 0090-9556, 8 p.Article

Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 InductionMAGANG SHOU; HAYASHI, Mike; PAN, Yvonne et al.Drug metabolism and disposition. 2008, Vol 36, Num 11, pp 2355-2370, issn 0090-9556, 16 p.Article

Cytochrome P450 Expression and Regulation in CYP3A4/CYP2D6 Double Transgenic Humanized MiceFELMLEE, Melanie A; LON, Hoi-Kei; GONZALEZ, Frank J et al.Drug metabolism and disposition. 2008, Vol 36, Num 2, pp 435-441, issn 0090-9556, 7 p.Article

INHIBITEURS ET SUBSTRATS DE L'ISOENZYME CYP 3A4 du CYTOCHROME P450 = Inhibitors and substrates of CYP3A4 isozymeLa Revue Prescrire. 2007, Vol 27, Num 290, pp 198-198, issn 0247-7750, 1 p., SUPArticle

Transcriptional repression of hepatic Cytochrome P450 3A4 gene in the presence of cancer. CommentaryCHARLES, Kellie A; RIVORY, Laurent P; BROWN, Sandie L et al.Clinical cancer research. 2006, Vol 12, Num 24, issn 1078-0432, 7492-7497, 7203-7204 [7 p.]Article

A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in VitroFAHMI, Odette A; MAURER, Tristan S; KISH, Mary et al.Drug metabolism and disposition. 2008, Vol 36, Num 8, pp 1698-1708, issn 0090-9556, 11 p.Article

Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 In VivoTEMPLETON, I. E; THUMMEL, K. E; KHARASCH, E. D et al.Clinical pharmacology and therapeutics. 2008, Vol 83, Num 1, pp 77-85, issn 0009-9236, 9 p.Article

Influence du jus de pamplemousse sur la toxicité des statines en pratique clinique = Effects of grapefruit juice on the toxicity of statins in clinical practiceMOULY, Stéphane; MAHE, Isabelle; JARRIN, Irène et al.STV. Sang thrombose vaisseaux. 2004, Vol 16, Num 5, pp 249-252, issn 0999-7385, 4 p.Article

Effects of Spice Constituents on P-Glycoprotein-Mediated Transport and CYP3A4-Mediated Metabolism in VitroWENXIA ZHANG; LIM, Lee-Yong.Drug metabolism and disposition. 2008, Vol 36, Num 7, pp 1283-1290, issn 0090-9556, 8 p.Article

Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomesMURAYAMA, Norie; IMAI, Naoko; NAKANE, Takahisa et al.Biochemical pharmacology. 2007, Vol 73, Num 12, pp 2020-2026, issn 0006-2952, 7 p.Article

Mini-series: I. Basic science. Uncertainty and inaccuracy of predicting CYP-mediated in vivo drug interactions in the ICU from in vitro models: focus on CYP3A4MOULY, Stéphane; MEUNE, Christophe; BERGMANN, Jean-Francois et al.Intensive care medicine (Print). 2009, Vol 35, Num 3, pp 417-429, issn 0342-4642, 13 p.Article

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